CELL QUESTION 1993:					L. PETERSON/AP BIOLOGY
	Membranes are important structural features of cells.
	   (a) Describe how membrane structure is related to the transport 
	          of materials across a membrane.
	   (b) Describe the role of membranes in the synthesis of ATP in either
	          respiration or photosynthesis.

Membranes serve diverse functions in eukaryotic and prokaryotic cells. One important role is to regulate the movement of materials into and out of cells. The phospholipid bilayer structure (fluid mosaic model) with specific membrane proteins accounts for the selective permeability of the membrane and passive and active transport mechanisms. In addition, membranes in prokaryotes and in the mitochondria and chloroplasts of eukaryotes facilitate the synthesis of ATP through chemiosmosis. PART A. (6 Maximum) Membrane Structure (3 Internal Maximum) __ Phospholipid structure - hydrophilic, hydrophobic, amphipathic __ Phospholipid bilayer / fluid mosaic description __ Proteins embedded in the membrane __ Sterols embedded in the membrane __ Well-labeled diagram may replace one of the above Membrane Transport (3 Internal Maximum) __ Use of the term "selectively permeable" or a good definition of selective permeability or an explanation of the role of phospholipids or proteins including nuclear pore proteins in determining selective permeability __ Description of the effect of size, charge, polarity, lipid solubility on membrane permeability Mechanisms + description related to structure: __ Passive transport: diffusion / osmosis + reference to membrane gradient __ Ion channel: transport as a mechanism for a change in permeability __ Facilitated diffusion: description (symport, antiport, uniport) __ Active transport: description __ Exocytosis, endocytosis, phagocytosis, pinocytosis: description (1 pt additional) A good example of one of the above mechanisms PART B. Role of the Membrane in the Production of ATP in Photosynthesis or Respiration (6 Maximum) Chemiosmosis: __ Involved molecules are embedded in the membrane __ Electron carriers are sequentially organized __ The energy comes from the flow of electrons __ H+ / Proton / pH gradient established __ Movement through the membrane generates ATP __ A specific protein makes ATP
RESPIRATION or PHOTOSYNTHESIS __ Site is the mitochondrion __ Site is the chloroplast __ Inner mitochondrial membrane __ Thylakoid / grana membranes (cristae) are involved in eukaryotes are involved in eukaryotes __ Folded membrane present __ Folded membrane present __ Cell membrane is involved in __ Thylakoid / grana membranes prokaryotes involved in prokaryotes __ Correct direction of H+ flow __ Correct direction of H+ flow